MrIIIE precursor (P01081) Protein Card

General Information
Name MrIIIE precursor
Alternative name(s) Mr3.4,Mr3.7
Organism Conus marmoreus
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Precursor
Notes In the ncbi cards Mr3.4 is found as a synonym for MrIIIE but a different Mr3.4 conotoxin, naturally occurring in Conus Marmoreus, already exists.

Classification
Conopeptide class conotoxin
Gene superfamily M superfamily
Pharmacological family

Sequence
MLKMGVVLFIVLVLFPLATLQLDA
DQPVERYAENKRLLNPD
ERRGIILHALGQR
VCCPFGGCHELCYCCD
G
Sequence region
[1-24]signal sequence
[55-70]mature peptideMrIIIE

References
Han,Y.H., Wang,Q., Jiang,H., Liu,L., Xiao,C., Yuan,D.D., Shao,X.X., Dai,Q.Y., Cheng,J.S. and Chi,C.W. (2006) Characterization of novel M-superfamily conotoxins with new disulfide linkage FEBS J. 273:4972-4982
Du,W.H., Han,Y.H., Huang,F.J., Li,J., Chi,C.W. and Fang,W.H. (2007) Solution structure of an M-1 conotoxin with a novel disulfide linkage FEBS J. 274:2596-2602
Wang,Q., Jiang,H., Han,Y.H., Yuan,D.D. and Chi,C.W. (2008) Two different groups of signal sequence in M-superfamily conotoxins. Toxicon 51:813-822

Internal links
Nucleic acids Conus marmoreus M conotoxin Mr3.4 mRNA, complete cds
Structure

External links
UniProtKB/Swiss-Prot Q5EHP3
Ncbi Q5EHP3, AAW78560

Tools