Mr3.8 precursor (P01082) Protein Card

General Information
Name Mr3.8 precursor
Alternative name(s) Mr044
Organism Conus marmoreus
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Precursor

Classification
Conopeptide class conotoxin
Gene superfamily M superfamily
Pharmacological family

Sequence
MLKMGVVLFIFLVLFPLATLQLDA
DQPVERYAKNKQLFNPH
KRRGIILRAPGKR
CCHWNWCDHLCSCCGS
Sequence region
[1-24]signal sequence
[55-70]mature peptideMr3.8

References
Han,Y.H., Wang,Q., Jiang,H., Liu,L., Xiao,C., Yuan,D.D., Shao,X.X., Dai,Q.Y., Cheng,J.S. and Chi,C.W. (2006) Characterization of novel M-superfamily conotoxins with new disulfide linkage FEBS J. 273:4972-4982
Wang,Q., Jiang,H., Han,Y.H., Yuan,D.D. and Chi,C.W. (2008) Two different groups of signal sequence in M-superfamily conotoxins. Toxicon 51:813-822
Dutertre,S., Jin,A.H., Kaas,Q., Jones,A., Alewood,P.F. and Lewis,R.J. (2013) Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom. Mol. Cell Proteomics 12:312-329
Lavergne,V., Dutertre,S., Jin,A.H., Lewis,R.J. and Alewood,P.F. (2013) Systematic interrogation of the Conus marmoreus venom duct transcriptome with ConoSorter reveals 158 novel conotoxins and 13 new gene superfamilies. BMC Genomics 14:708

Internal links
Nucleic acids Conus marmoreus M conotoxin Mr3.8 mRNA, complete cds
Structure

External links
UniProtKB/Swiss-Prot Q5EHP2
Ncbi BAO02128 (partial), Q5EHP2, AAW78561

Tools