Ca1.2 precursor (P00013) Protein Card

General Information
Name Ca1.2 precursor
Alternative name(s) Ca-4
Organism Conus caracteristicus
Organism region Indo-Pacific
Organism diet vermivorous
Protein Type Precursor
Notes The mature peptide region is from Santos et al., the only reference, and differs from the annotation in the Swiss-prot card.

Classification
Conopeptide class conotoxin
Gene superfamily A superfamily
Pharmacological family

Sequence
MGMRMMFTVFLLVVLATTVVS
FTSDRASEGRNAAAKDKASD
LVALTVR
GCCAIRECRLQNAAYCGGIY
Sequence evidence nucleic acid level
Sequence region
[1-21]signal sequence
[49-68]mature peptideCa1.2

References
Santos,A.D., McIntosh,J.M., Hillyard,D.R., Cruz,L.J. and Olivera,B.M. (2004) The A-superfamily of conotoxins: structural and functional divergence J. Biol. Chem. 279:17596-17606
Yao, G., Peng, C., Zhu, Y., Fan, C., Jiang, H., Chen, J., Cao, Y. and Shi, Q. (2019) High-Throughput Identification and Analysis of Novel Conotoxins from Three Vermivorous Cone Snails by Transcriptome Sequencing Marine drugs 17:193

Internal links
Nucleic acids Alpha-conotoxin peptides
Sequence 84 from patent US 6797808
Structure

External links
UniProtKB/Swiss-Prot P0C1W0
Ncbi P0C1W0

Tools