Contryphan-Sm precursor (P01311) Protein Card

General Information
Name Contryphan-Sm precursor
Organism Conus stercusmuscarum
Organism region Indo-Pacific
Organism diet piscivorous
Protein Type Precursor

Classification
Conopeptide class contryphan
Gene superfamily O2 superfamily
Pharmacological family

Sequence
MGKLTILVLVAAVLLSTQVMVQG
DADQPADRDAVPRDDNPS
GTDGKFMNVLRRF
GCPWQPWC
G
Sequence region
[1-23]signal sequence
[55-62]mature peptideContryphan-Sm

References
Pallaghy,P.K., He,W., Jimenez,E.C., Olivera,B.M. and Norton,R.S. (2000) Structures of the contryphan family of cyclic peptides. Role of electrostatic interactions in cis-trans isomerism Biochemistry 39:12845-12852
Jacobsen,R., Jimenez,E.C., Grilley,M., Watkins,M., Hillyard,D., Cruz,L.J. and Olivera,B.M. (1998) The contryphans, a D-tryptophan-containing family of Conus peptides: interconversion between conformers J. Pept. Res. 51:173-179

Internal links
Nucleic acids Sequence 9 from patent US 6077934
Sequence 9 from patent US 6153738
Structure

External links
UniProtKB/Swiss-Prot P58787
Ncbi P58787

Tools