Gla(1)-TxVI (P01511) Protein Card

General Information
Name Gla(1)-TxVI
Organism Conus textile (Cloth-of-gold cone)
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Wild type
Protein precursor Gla(1)-TxVI precursor (703)

Classification
Conopeptide class conotoxin
Gene superfamily O2 superfamily
Cysteine framework VI/VII
Pharmacological family

Sequence
GM(BTr)G(Gla)CKDGLTTCLAOS(Gla)CCS(Gla)DC(Gla)
GSCTM(BTr)
Modified residues
positionsymbolname
3BTrBromotryptophan
5GlaGamma carboxylic glutamic acid
16O4-Hydroxyproline
18GlaGamma carboxylic glutamic acid
22GlaGamma carboxylic glutamic acid
25GlaGamma carboxylic glutamic acid
31BTrBromotryptophan
Sequence evidence protein level
Average Mass 3677.50
Monoisotopic Mass 3672.93
Isoelectric Point 1.74
Extinction Coefficient [280nm] NA

References
Kalume,D.E., Stenflo,J., Czerwiec,E., Hambe,B., Furie,B.C., Furie,B. and Roepstorff,P. (2000) Structure determination of two conotoxins from Conus textile by a combination of matrix-assisted laser desorption/ionization time-of-flight and electrospray ionization mass spectrometry and biochemical methods J Mass Spectrom 35:145-156

Internal links
Protein Precursor Gla(1)-TxVI precursor (703)
Nucleic acids
Structure

External links
UniProtKB/Swiss-Prot P58922
Ncbi P58922

Tools