TxVIIA (P01517) Protein Card

General Information
Name TxVIIA
Alternative name(s) TxIIA
Organism Conus textile (Cloth-of-gold cone)
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Wild type
Protein precursor TxVIIA precursor (707)
TxVIIA precursor (706)
Notes This peptide was first published with an incomplete sequence under the name TxIIA.

Classification
Conopeptide class conotoxin
Gene superfamily O2 superfamily
Cysteine framework VI/VII
Pharmacological family gamma conotoxin

Sequence
CGGYSTYC(Gla)VDS(Gla)CCSDNCVRSYCTLF(nh2)
Modified residues
positionsymbolname
9GlaGamma carboxylic glutamic acid
13GlaGamma carboxylic glutamic acid
28nh2C-term amidation
Sequence evidence protein level
Average Mass 3089.27
Monoisotopic Mass 3087.04
Isoelectric Point 2.20
Extinction Coefficient [280nm] 4470.00

References
Fainzilber,M., Gordon,D., Hasson,A., Spira,M.E. and Zlotkin,E. (1991) Mollusc-specific toxins from the venom of Conus textile neovicarius Eur. J. Biochem. 202:589-595
Nakamura,T., Yu,Z., Fainzilber,M. and Burlingame,A.L. (1996) Mass spectrometric-based revision of the structure of a cysteine-rich peptide toxin with gamma-carboxyglutamic acid, TxVIIA, from the sea snail, Conus textile Protein Sci. 5:524-530

Internal links
Protein Precursor TxVIIA precursor (707)
TxVIIA precursor (706)
Nucleic acids
Structure

External links
UniProtKB/Swiss-Prot P24160
Ncbi P24160, AAB20786

Tools