TxVII (P01603) Protein Card

General Information
Name TxVII
Organism Conus textile (Cloth-of-gold cone)
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Wild type
Protein precursor TxVII precursor (1096)
TxVII precursor (1097)
Notes L-Type Calcium Channel Blocker

Classification
Conopeptide class conotoxin
Gene superfamily O1 superfamily
Cysteine framework VI/VII
Pharmacological family omega conotoxin

Sequence
CKQADEPCDVFSLDCCTGICLGVCMW
Sequence evidence protein level
Average Mass 2834.28
Monoisotopic Mass 2832.08
Isoelectric Point 4.03
Extinction Coefficient [280nm] 5500.00

References
Fainzilber,M., Lodder,J.C., van der Schors,R.C., Li,K.W., Yu,Z., Burlingame,A.L., Geraerts,W.P. and Kits,K.S. (1996) A novel hydrophobic omega-conotoxin blocks molluscan dihydropyridine-sensitive calcium channels Biochemistry 35:8748-8752
Kobayashi,K., Sasaki,T., Sato,K. and Kohno,T. (2000) Three-dimensional solution structure of omega-conotoxin TxVII, an L-type calcium channel blocker Biochemistry 39:14761-14767

Internal links
Protein Precursor TxVII precursor (1096)
TxVII precursor (1097)
Nucleic acids
Structure THREE-DIMENSIONAL SOLUTION STRUCTURE OF OMEGA-CONOTOXIN TXVII, AN L-TYPE CALCIUM CHANNEL BLOCKER

External links
UniProtKB/Swiss-Prot P56714
Ncbi 1F3K_A, P56714

Tools