PnVIIA (P01636) Protein Card

General Information
Name PnVIIA
Alternative name(s) Pn7a
Organism Conus pennaceus
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Wild type
Protein precursor PnVIIA precursor (716)

Classification
Conopeptide class conotoxin
Gene superfamily O2 superfamily
Cysteine framework VI/VII
Pharmacological family gamma conotoxin

Sequence
DCTSWFGRCTVNS(Gla)CCSNSCDQTYC(Gla)LYAFOS
Modified residues
positionsymbolname
14GlaGamma carboxylic glutamic acid
26GlaGamma carboxylic glutamic acid
31O4-Hydroxyproline
Sequence evidence protein level
Average Mass 3718.90
Monoisotopic Mass 3716.29
Isoelectric Point 2.46
Extinction Coefficient [280nm] 8480.00

References
Fainzilber,M., Nakamura,T., Lodder,J.C., Zlotkin,E., Kits,K.S. and Burlingame,A.L. (1998) gamma-Conotoxin-PnVIIA, a gamma-carboxyglutamate-containing peptide agonist of neuronal pacemaker cation currents Biochemistry 37:1470-1477

Internal links
Protein Precursor PnVIIA precursor (716)
Nucleic acids
Structure

External links
UniProtKB/Swiss-Prot P56711
Ncbi P56711

Tools