Conorphin-T precursor (P01678) Protein Card

General Information
Name Conorphin-T precursor (named by ConoServer)
Alternative name(s) TeAr193 precursor
Organism Conus textile (Cloth-of-gold cone)
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Precursor

Classification
Conopeptide class conotoxin
Gene superfamily T superfamily
Pharmacological family

Sequence
MRCLPVFVILLLLIASAPSVDA
QPKTKDDIPQASFLDNAKR
YLQVLESKR
NCCRRQICC
GRT
K
Sequence region
[1-22]signal sequence
[51-62]mature peptide
[51-59]mature peptideConorphin-T[bead]
[51-59]mature peptideConorphin-T[globular]
[51-59]mature peptideConorphin-T[ribbon]

References
Luo,S., Zhangsun,D., Zhang,B., Chen,X. and Feng,J. (2006) Direct cDNA cloning of novel conotoxins of the T-superfamily from Conus textile Peptides 27:2640-2646
Bhatia,S., Kil,Y.J., Ueberheide,B., Chait,B.T., Tayo,L., Cruz,L., Lu,B., Yates,J.R. 3rd. and Bern,M. (2012) Constrained de novo sequencing of conotoxins. J. Proteome Res. 11:4191-4200
Brust A., Croker D. E., Colless B., Ragnarsson L., Andersson A., Jain K., Garcia-Caraballo S., Castro J., Brierley S. M., Alewood P. F., Lewis R. J. (2016) Conopeptide-Derived κ-Opioid Agonists (Conorphins): Potent, Selective, and Metabolic Stable Dynorphin A Mimetics with Antinociceptive Properties J. Med. Chem.

Internal links
Nucleic acids Conus textile T superfamily conotoxin TeAr193 precursor, gene, complete cds.
Structure

External links
UniProtKB/Swiss-Prot Q3YEH2
Ncbi Q3YEH2

Tools