MrIB (P01737) Protein Card

General Information
Name MrIB
Alternative name(s) Mr1b
Organism Conus marmoreus
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Wild type
Notes The superfamily was assigned on the strong sequence identity with MrIA.

Classification
Conopeptide class conotoxin
Gene superfamily T superfamily
Cysteine framework X
Pharmacological family chi conotoxin

Sequence
VGVCCGYKLCHOC
Modified residues
positionsymbolname
12O4-Hydroxyproline
Sequence evidence protein level
Average Mass 1393.67
Monoisotopic Mass 1392.54
Isoelectric Point 10.34
Extinction Coefficient [280nm] 1490.00

Synthetic variants
MrIB C-term amidatedVGVCCGYKLCHOC(nh2)

References
Sharpe,I.A., Gehrmann,J., Loughnan,M.L., Thomas,L., Adams,D.A., Atkins,A., Palant,E., Craik,D.J., Adams,D.J., Alewood,P.F. and Lewis,R.J. (2001) Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter Nat. Neurosci. 4:902-907

Internal links
Nucleic acids
Structure

External links
UniProtKB/Swiss-Prot P58810
Ncbi P58810

Tools