De13a (P02550) Protein Card

General Information
Name De13a
Alternative name(s) DeXIIIA
Organism Conus delessertii
Organism region Western Atlantic and Caribbean
Organism diet vermivorous
Protein Type Wild type
Protein precursor De13a precursor (1500)
Notes Position 5 is a serine in Aguilar et al 2005 but is an arginine in the ncbi card.

Classification
Conopeptide class conotoxin
Gene superfamily
Cysteine framework XIII
Pharmacological family

Sequence
DCOTSCOTTCANG(BTr)ECC(hLy)GYOCVN(hLy)ACSG
CTH(nh2)
Modified residues
positionsymbolname
3O4-Hydroxyproline
7O4-Hydroxyproline
14BTrBromotryptophan
18hLy5-hydroxy-lysine
21O4-Hydroxyproline
25hLy5-hydroxy-lysine
33nh2C-term amidation
Sequence evidence protein level
Average Mass 3490.61
Monoisotopic Mass 3487.09
Isoelectric Point 5.52
Extinction Coefficient [280nm] 1490.00

References
Aguilar,M.B., López-Vera,E., Ortiz,E., Becerril,B., Possani,L.D., Olivera,B.M. and Heimer de la Cotera,E.P. (2005) A novel conotoxin from Conus delessertii with posttranslationally modified lysine residues Biochemistry 44:11130-11136

Internal links
Protein Precursor De13a precursor (1500)
Nucleic acids
Structure

External links
Ncbi P84698

Tools