TxX (P02551) Protein Card

General Information
Name TxX
Organism Conus textile (Cloth-of-gold cone)
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Wild type
Protein precursor TxX precursor (1056)

Classification
Conopeptide class conotoxin
Gene superfamily I2 superfamily
Cysteine framework XII
Pharmacological family

Sequence
SCDS(Gla)FSS(Gla)FC(Gla)RP(Gla)(Gla)SCSCS
THTCCHWARRDQCMKPQRCISAQKGN(nh2)
Modified residues
positionsymbolname
5GlaGamma carboxylic glutamic acid
9GlaGamma carboxylic glutamic acid
12GlaGamma carboxylic glutamic acid
15GlaGamma carboxylic glutamic acid
16GlaGamma carboxylic glutamic acid
48nh2C-term amidation
Sequence evidence protein level
Average Mass 5600.94
Monoisotopic Mass 5597.07
Isoelectric Point 6.81
Extinction Coefficient [280nm] 5500.00

References
Brown,M.A., Begley,G.S., Czerwiec,E., Stenberg,L.M., Jacobs,M., Kalume,D.E., Roepstorff,P., Stenflo,J., Furie,B.C. and Furie,B. (2005) Precursors of novel Gla-containing conotoxins contain a carboxy-terminal recognition site that directs gamma-carboxylation Biochemistry 44:9150-9159

Internal links
Protein Precursor TxX precursor (1056)
Nucleic acids
Structure

External links
Ncbi Q5I4E6, AAW50949

Tools