TxIIIB (P02563) Protein Card

General Information
Name TxIIIB
Alternative name(s) Tx3.3,Tx3b
Organism Conus textile (Cloth-of-gold cone)
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Wild type
Protein precursor TxIIIB precursor (1401)
Notes Bhatia 2012 found that the methionine residue could be oxidised.

Classification
Conopeptide class conotoxin
Gene superfamily M superfamily
Cysteine framework III
Pharmacological family

Sequence
CCPPVACNMGCKPCC(nh2)
Modified residues
positionsymbolname
16nh2C-term amidation
Sequence evidence protein level
Average Mass 1521.88
Monoisotopic Mass 1520.50
Isoelectric Point 10.95
Extinction Coefficient [280nm] NA

References
Corpuz,G.P., Jacobsen,R.B., Jimenez,E.C., Watkins,M., Walker,C., Colledge,C., Garrett,J.E., McDougal,O., Li,W., Gray,W.R., Hillyard,D.R., Rivier,J., McIntosh,J.M., Cruz,L.J. and Olivera,B.M. (2005) Definition of the M-conotoxin superfamily: characterization of novel peptides from molluscivorous Conus venoms Biochemistry 44:8176-8186
Bhatia,S., Kil,Y.J., Ueberheide,B., Chait,B.T., Tayo,L., Cruz,L., Lu,B., Yates,J.R. 3rd. and Bern,M. (2012) Constrained de novo sequencing of conotoxins. J. Proteome Res. 11:4191-4200

Internal links
Protein Precursor TxIIIB precursor (1401)
Nucleic acids
Structure

External links
Ncbi P0C1N8

Tools