contulakin-G (P02618) Protein Card

General Information
Name contulakin-G
Alternative name(s) CGX-1160
Organism Conus geographus (Geography cone)
Organism region Indo-Pacific
Organism diet piscivorous
Protein Type Wild type
Protein precursor contulakin-G precursor (1263)
contulakin-G precursor (1323)
Notes Motor control-associated dysfunction in mice (intracranial injection) [Craig 1999]. Bind to human and rat neurotensin receptors [Craig 1999]. The non-glycosylated form is 10-fold less active [Craig 1999].

Classification
Conopeptide class contulakin
Gene superfamily C superfamily
Pharmacological family

Sequence
ZSEEGGSNA(gTr)KKPYIL
Modified residues
positionsymbolname
1ZPyroglutamic acid
10gTrglycosylated threonine
Sequence evidence protein level
Average Mass 2070.19
Monoisotopic Mass 2068.97
Isoelectric Point NA
Extinction Coefficient [280nm] NA

References
Craig,A.G., Norberg,T., Griffin,D., Hoeger,C., Akhtar,M., Schmidt,K., Low,W., Dykert,J., Richelson,E., Navarro,V., Mazella,J., Watkins,M., Hillyard,D., Imperial,J., Cruz,L.J. and Olivera,B.M. (1999) Contulakin-G, an O-glycosylated invertebrate neurotensin J. Biol. Chem. 274:13752-13759

Internal links
Protein Precursor contulakin-G precursor (1263)
contulakin-G precursor (1323)
Nucleic acids
Structure contulakin-G

External links
Ncbi Q9XYR5, AAD30031

Tools