Gla-MrIV (P02693) Protein Card

General Information
Name Gla-MrIV
Alternative name(s) Mr5.3
Organism Conus marmoreus
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Wild type
Protein precursor Gla-MrIV precursor (858)
Notes Hansson et al. and Han et al. disagree about the presence of the gamma carboxylic acids. The Hansson et al. definition is here used according to the ncbi card.

Classification
Conopeptide class conotoxin
Gene superfamily T superfamily
Cysteine framework V
Pharmacological family

Sequence
CCITF(Gla)SCC(Gla)FDL
Modified residues
positionsymbolname
6GlaGamma carboxylic glutamic acid
10GlaGamma carboxylic glutamic acid
Sequence evidence protein level
Average Mass 1596.72
Monoisotopic Mass 1595.49
Isoelectric Point 1.96
Extinction Coefficient [280nm] NA

References
Han,Y.H., Wang,Q., Jiang,H., Miao,X.W., Chen,J.S. and Chi,C.W. (2005) Sequence diversity of T-superfamily conotoxins from Conus marmoreus Toxicon 45:481-487
Hansson,K., Furie,B., Furie,B.C. and Stenflo,J. (2004) Isolation and characterization of three novel Gla-containing Conus marmoreus venom peptides, one with a novel cysteine pattern Biochem. Biophys. Res. Commun. 319:1081-1087

Internal links
Protein Precursor Gla-MrIV precursor (858)
Nucleic acids
Structure

External links
Ncbi Q6PN83, AAT01631

Tools