MrIIIE (P02697) Protein Card

General Information
Name MrIIIE
Alternative name(s) Mr042,Mr3e
Organism Conus marmoreus
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Wild type
Protein precursor MrIIIE precursor (1081)
MrIIIE precursor (5429)
MrIIIE precursor (6196)
MrIIIE precursor (6175)
MrIIIE precursor (6209)
Notes In a ncbi card the name Mr3.4 is synonymous to MrIIIE but the name Mr3.4 was already used previously to describe another peptide from Conus marmoreus.

Classification
Conopeptide class conotoxin
Gene superfamily M superfamily
Cysteine framework III
Pharmacological family

Sequence
VCCPFGGCHELCYCCD(nh2)
Modified residues
positionsymbolname
17nh2C-term amidation
Sequence evidence protein level
Average Mass 1745.01
Monoisotopic Mass 1743.54
Isoelectric Point 5.52
Extinction Coefficient [280nm] 1490.00

References
Han,Y.H., Wang,Q., Jiang,H., Liu,L., Xiao,C., Yuan,D.D., Shao,X.X., Dai,Q.Y., Cheng,J.S. and Chi,C.W. (2006) Characterization of novel M-superfamily conotoxins with new disulfide linkage FEBS J. 273:4972-4982
Du,W.H., Han,Y.H., Huang,F.J., Li,J., Chi,C.W. and Fang,W.H. (2007) Solution structure of an M-1 conotoxin with a novel disulfide linkage FEBS J. 274:2596-2602
Wang,Q., Jiang,H., Han,Y.H., Yuan,D.D. and Chi,C.W. (2008) Two different groups of signal sequence in M-superfamily conotoxins. Toxicon 51:813-822
Dutertre,S., Jin,A.H., Kaas,Q., Jones,A., Alewood,P.F. and Lewis,R.J. (2013) Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom. Mol. Cell Proteomics 12:312-329

Internal links
Protein Precursor MrIIIE precursor (1081)
MrIIIE precursor (5429)
MrIIIE precursor (6196)
MrIIIE precursor (6175)
MrIIIE precursor (6209)
Nucleic acids
Structure SOLUTION STRUCTURE OF AN M-1 CONOTOXIN WITH A NOVEL DISULFIDE LINKAGE

External links
Ncbi 2EFZ, Q5EHP3, AAW78560

Tools