Gla(2)-TxVI/B (P02846) Protein Card

General Information
Name Gla(2)-TxVI/B
Organism Conus textile (Cloth-of-gold cone)
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Wild type
Protein precursor Gla(2)-TxVI/B precursor (4493)
Notes The superfamily assignment is based on the close homology with Gla(2)-TxVI/A (Czerwiec et al. 20006).

Classification
Conopeptide class conotoxin
Gene superfamily O2 superfamily
Cysteine framework VI/VII
Pharmacological family

Sequence
NCSDDWQYC(Gla)SOTDCCSWDCDVVCS(nh2)
Modified residues
positionsymbolname
10GlaGamma carboxylic glutamic acid
12O4-Hydroxyproline
26nh2C-term amidation
Sequence evidence protein level
Average Mass 2917.00
Monoisotopic Mass 2914.88
Isoelectric Point 1.09
Extinction Coefficient [280nm] 12490.00

References
Czerwiec,E., Kalume,D.E., Roepstorff,P., Hambe,B., Furie,B., Furie,B.C. and Stenflo,J. (2006) Novel gamma-carboxyglutamic acid-containing peptides from the venom of Conus textile. FEBS J. 273:2779-2788

Internal links
Protein Precursor Gla(2)-TxVI/B precursor (4493)
Nucleic acids
Structure

External links

Tools