Ai1.2 (P02944) Protein Card

General Information
Name Ai1.2
Organism Conus ammiralis
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Wild type
Protein precursor Ai1.2 precursor (2945)
Notes Does not inhibit calcium currents in rat DRG neurons. (Carstens et al, 2016)

Classification
Conopeptide class conotoxin
Gene superfamily A superfamily
Cysteine framework I
Pharmacological family

Sequence
PECCSDPRCNSTHPELCG
Sequence evidence nucleic acid level
Average Mass 1944.10
Monoisotopic Mass 1942.71
Isoelectric Point 4.80
Extinction Coefficient [280nm] NA

References
Carstens,B.B., Berecki,G., Daniel,J.T., Lee,H.S., Jackson,K.A., Tae,H.S., Sadeghi,M., Castro,J., O (2016) Structure-Activity Studies of Cysteine-Rich a-Conotoxins that Inhibit High-Voltage-Activated Calcium Channels via GABA(B) Receptor Activation Reveal a Minimal Functional Motif. Angew. Chem. Int. Ed. Engl 55:4692-4696

Internal links
Protein Precursor Ai1.2 precursor (2945)
Nucleic acids
Structure

External links

Tools