TxMEKL-P2 (P03212) Protein Card

General Information
Name TxMEKL-P2
Organism Conus textile (Cloth-of-gold cone)
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Wild type
Protein precursor TxMEKL-P2 precursor (715)

Classification
Conopeptide class conotoxin
Gene superfamily O2 superfamily
Cysteine framework VI/VII
Pharmacological family

Sequence
DCRGYDAOCSSGAPCCD(BTr)(BTr)TCSARTNRCF
Modified residues
positionsymbolname
8O4-Hydroxyproline
18BTrBromotryptophan
19BTrBromotryptophan
Sequence evidence protein level
Average Mass 3400.31
Monoisotopic Mass 3396.00
Isoelectric Point 8.31
Extinction Coefficient [280nm] 1490.00

References
Ueberheide,B.M., Fenyƶ,D., Alewood,P.F. and Chait,B.T. (2009) Rapid sensitive analysis of cysteine rich peptide venom components. Proc. Natl. Acad. Sci. U.S.A. 106:6910-6915
Bhatia,S., Kil,Y.J., Ueberheide,B., Chait,B.T., Tayo,L., Cruz,L., Lu,B., Yates,J.R. 3rd. and Bern,M. (2012) Constrained de novo sequencing of conotoxins. J. Proteome Res. 11:4191-4200
Dobson,R., Collodoro,M., Gilles,N., Turtoi,A., De Pauw,E. and Quinton,L. (2012) Secretion and maturation of conotoxins in the venom ducts of Conus textile. Toxicon 60:1370-1379

Internal links
Protein Precursor TxMEKL-P2 precursor (715)
Nucleic acids
Structure

External links

Tools