Conopressin-T (P03556) Protein Card

General Information
Name Conopressin-T
Organism Conus tulipa (tulip cone)
Organism region Indo-Pacific
Organism diet piscivorous
Protein Type Wild type
Notes Selective V1a receptor antagonist [Dutertre 2008]

Classification
Conopeptide class conopressin
Gene superfamily
Pharmacological family

Sequence
CYIQNCLRV(nh2)
Modified residues
positionsymbolname
10nh2C-term amidation
Sequence evidence protein level
Average Mass 1108.34
Monoisotopic Mass 1107.53
Isoelectric Point 11.65
Extinction Coefficient [280nm] 1490.00

References
Croker D., Dutertre S., Alewood P., and Lewis R. (2006) Discovery and pharmacology of conopressin-T, a novel vasopressin-like peptide from Conus tulipa. Acta Pharmacologica Sinica 27:351-351
Dutertre,S., Croker,D., Daly,N.L., Andersson,A., Muttenthaler,M., Lumsden,N.G., Craik,D.J., Alewood,P.F., Guillon,G. and Lewis,R.J. (2008) Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptides. J. Biol. Chem. 283:7100-7108

Internal links
Nucleic acids
Structure Solution structure of conopressin-T

External links

Tools