ImI [C2Agl,C8Agl] (P03636) Protein Card

General Information
Name ImI [C2Agl,C8Agl]
Organism synthetic construct
Protein Type Synthetic
Parent ImI

Classification
Conopeptide class conotoxin
Gene superfamily
Pharmacological family

Sequence
G(Agl)CSDPR(Agl)AWRC(nh2)
Modified residues
positionsymbolname
2AglCarbabridge [C2 unsaturated] (half)
8AglCarbabridge [C2 unsaturated] (half)
13nh2C-term amidation
Average Mass 1343.54
Monoisotopic Mass 1342.60
Isoelectric Point 10.99
Extinction Coefficient [280nm] 5500.00

References
MacRaild,C.A., Illesinghe,J., van Lierop,B.J., Townsend,A.L., Chebib,M., Livett,B.G., Robinson,A.J. and Norton,R.S. (2009) Structure and activity of (2,8)-dicarba-(3,12)-cystino alpha-ImI, an alpha-conotoxin containing a nonreducible cystine analogue. J. Med. Chem. 52:755-762

Internal links
Nucleic acids
Structure Solution structure of dicarba-ImI: an alpha-conotoxin with a non-reducible cystine analogue

External links

Tools