Vc1.1[P6K] (P03662) Protein Card

General Information
Name Vc1.1[P6K]
Organism synthetic construct
Protein Type Synthetic
Parent Vc1.1

Classification
Conopeptide class conotoxin
Gene superfamily
Cysteine framework I
Pharmacological family alpha conotoxin

Sequence
GCCSDKRCNYDHPEIC(nh2)
Modified residues
positionsymbolname
17nh2C-term amidation
Average Mass 1838.03
Monoisotopic Mass 1836.68
Isoelectric Point 6.62
Extinction Coefficient [280nm] 1490.00

References
Halai,R., Clark,R.J., Nevin,S.T., Jensen,J.E., Adams,D.J. and Craik,D.J. (2009) Scanning mutagenesis of alpha-conotoxin Vc1.1 reveals residues crucial for activity at the alpha9alpha10 nicotinic acetylcholine receptor. J. Biol. Chem.
Sadeghi M, Carstens BB, Callaghan BP, Daniel JT, Tae HS, O Donnell T, Castro J, Brierley SM, Adams DJ, Craik DJ, Clark RJ (2018) Structure-Activity Studies Reveal the Molecular Basis for GABAB-Receptor Mediated Inhibition of High Voltage-Activated Calcium Channels by α-Conotoxin Vc1.1. ACS Chem. Biol. 13:1577-1587

Internal links
Nucleic acids
Structure

External links

Tools