Tx1c (P03753) Protein Card

General Information
Name Tx1c (named by ConoServer)
Alternative name(s) conotoxin 1
Organism Conus textile (Cloth-of-gold cone)
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Wild type
Notes The sequence of this toxin was determined by mass spectrometry only and there is an uncertainty between isoleucine and leucine residues.

Classification
Conopeptide class conotoxin
Gene superfamily
Cysteine framework I
Pharmacological family

Sequence
GCCSRPPCIANNPDIC(nh2)
Modified residues
positionsymbolname
17nh2C-term amidation
Sequence evidence protein level
Average Mass 1657.91
Monoisotopic Mass 1656.66
Isoelectric Point 7.00
Extinction Coefficient [280nm] NA

References
Ueberheide,B.M., Fenyƶ,D., Alewood,P.F. and Chait,B.T. (2009) Rapid sensitive analysis of cysteine rich peptide venom components. Proc. Natl. Acad. Sci. U.S.A. 106:6910-6915
Bhatia,S., Kil,Y.J., Ueberheide,B., Chait,B.T., Tayo,L., Cruz,L., Lu,B., Yates,J.R. 3rd. and Bern,M. (2012) Constrained de novo sequencing of conotoxins. J. Proteome Res. 11:4191-4200

Internal links
Nucleic acids
Structure

External links
UniProtKB/Swiss-Prot P86261
Ncbi P86261

Tools