Tx10c (P03754) Protein Card

General Information
Name Tx10c (named by ConoServer)
Alternative name(s) conotoxin 2
Organism Conus textile (Cloth-of-gold cone)
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Wild type
Notes Bhatia 2012 did not find the modification of glutamine to pyroglutamic acid.

Classification
Conopeptide class conotoxin
Gene superfamily
Cysteine framework X
Pharmacological family

Sequence
ZTCCGYRMCVOC(nh2)
Modified residues
positionsymbolname
1ZPyroglutamic acid
11O4-Hydroxyproline
13nh2C-term amidation
Sequence evidence protein level
Average Mass 1357.60
Monoisotopic Mass 1356.45
Isoelectric Point NA
Extinction Coefficient [280nm] NA

References
Ueberheide,B.M., Fenyƶ,D., Alewood,P.F. and Chait,B.T. (2009) Rapid sensitive analysis of cysteine rich peptide venom components. Proc. Natl. Acad. Sci. U.S.A. 106:6910-6915
Bhatia,S., Kil,Y.J., Ueberheide,B., Chait,B.T., Tayo,L., Cruz,L., Lu,B., Yates,J.R. 3rd. and Bern,M. (2012) Constrained de novo sequencing of conotoxins. J. Proteome Res. 11:4191-4200

Internal links
Nucleic acids
Structure

External links
UniProtKB/Swiss-Prot P86257
Ncbi P86257

Tools