Tx5d (P03758) Protein Card

General Information
Name Tx5d (named by ConoServer)
Alternative name(s) Trixin
Organism Conus textile (Cloth-of-gold cone)
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Wild type
Notes The sequence determination (Ueberheide et al. 2009; Bhatia et al 2012) presents several ambiguities, the isoleucines could also be leucines.

Classification
Conopeptide class conotoxin
Gene superfamily
Cysteine framework V
Pharmacological family

Sequence
NIQIICCKHTPACCT(nh2)
Modified residues
positionsymbolname
16nh2C-term amidation
Sequence evidence protein level
Average Mass 1642.98
Monoisotopic Mass 1641.72
Isoelectric Point 9.95
Extinction Coefficient [280nm] NA

References
Ueberheide,B.M., Fenyƶ,D., Alewood,P.F. and Chait,B.T. (2009) Rapid sensitive analysis of cysteine rich peptide venom components. Proc. Natl. Acad. Sci. U.S.A. 106:6910-6915
Bhatia,S., Kil,Y.J., Ueberheide,B., Chait,B.T., Tayo,L., Cruz,L., Lu,B., Yates,J.R. 3rd. and Bern,M. (2012) Constrained de novo sequencing of conotoxins. J. Proteome Res. 11:4191-4200
Dobson,R., Collodoro,M., Gilles,N., Turtoi,A., De Pauw,E. and Quinton,L. (2012) Secretion and maturation of conotoxins in the venom ducts of Conus textile. Toxicon 60:1370-1379

Internal links
Nucleic acids
Structure

External links
UniProtKB/Swiss-Prot P86264
Ncbi P86264

Tools