RIIIKΔ9 (P04238) Protein Card

General Information
Name RIIIKΔ9
Organism synthetic construct
Protein Type Synthetic
Parent RIIIK

Classification
Conopeptide class conotoxin
Gene superfamily
Cysteine framework III
Pharmacological family kappa conotoxin

Sequence
LOSCCSLNLRLCOVOACKRNOCCT(nh2)
Modified residues
positionsymbolname
2O4-Hydroxyproline
13O4-Hydroxyproline
15O4-Hydroxyproline
21O4-Hydroxyproline
25nh2C-term amidation
Average Mass 2649.14
Monoisotopic Mass 2647.16
Isoelectric Point 12.54
Extinction Coefficient [280nm] NA

References
Chen,P., Dendorfer,A., Finol-Urdaneta,R.K., Terlau,H. and Olivera,B.M. (2010) Biochemical characterization of kM-RIIIJ, a KV1.2 channel blocker: Evaluation of cardioprotective effects of kM-conotoxins. J Biol Chem 285:14882-14889

Internal links
Nucleic acids
Structure

External links

Tools