Gly-AnIB (P04397) Protein Card

General Information
Name Gly-AnIB
Organism synthetic construct
Protein Type Synthetic
Parent AnIB

Classification
Conopeptide class conotoxin
Gene superfamily
Cysteine framework I
Pharmacological family alpha conotoxin

Sequence
GGGCCSHPACAANNQD(sTy)C(nh2)
Modified residues
positionsymbolname
17sTySulfotyrosine
19nh2C-term amidation
Average Mass 1844.92
Monoisotopic Mass 1843.53
Isoelectric Point 5.63
Extinction Coefficient [280nm] 1490.00

Activity

IC50: Nicotinic acetylcholine receptors

TargetOrganismIC50nhillAgonistRef
α3β2R. norvegicus200pM1.16100uM AchLoughnan,M.L. et al. (2004)

References
Loughnan,M.L., Nicke,A., Jones,A., Adams,D.J., Alewood,P.F. and Lewis,R.J. (2004) Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone J. Med. Chem. 47:1234-1241

Internal links
Nucleic acids
Structure

External links

Tools