Pc16a (P05219) Protein Card

General Information
Name Pc16a
Alternative name(s) Pc16b
Organism Conus pictus
Organism region South Africa
Protein Type Wild type
Notes Peigneur 2013 called Pc16b the non-amidated form of Pc16a.

Classification
Conopeptide class conotoxin
Gene superfamily
Cysteine framework XVI
Pharmacological family

Sequence
SCSCKRNFLCC(nh2)
Modified residues
positionsymbolname
12nh2C-term amidation
Sequence evidence protein level
Average Mass 1258.50
Monoisotopic Mass 1257.49
Isoelectric Point 11.81
Extinction Coefficient [280nm] -1.00

References
Van Der Haegen A, Peigneur S, Dyubankova N, Möller C, Marí F, Diego-García E, Naudé R, Lescrinier E, Herdewijn P, Tytgat J (2012) Pc16a, the first characterized peptide from Conus pictus venom, shows a novel disulfide connectivity Peptides 34:106-113
Peigneur,S., Van Der Haegen,A., Möller,C., Waelkens,E., Diego-García,E., Marí,F., Naudé,R. and Tytgat,J. (2013) Unraveling the peptidome of the South African cone snails Conus pictus and Conus natalis. Peptides 41:8-16

Internal links
Nucleic acids
Structure

External links
UniProtKB/Swiss-Prot P86942
Ncbi P86942, 2LER_A

Tools