MII [N5R,E11A,H12K] (P05527) Protein Card

General Information
Name MII [N5R,E11A,H12K]
Organism synthetic construct
Protein Type Synthetic
Notes It is unclear from McDougal 2013 if the peptide displays a C-terminal amidation or not.

Classification
Conopeptide class conotoxin
Gene superfamily
Cysteine framework I
Pharmacological family

Sequence
GCCSRPVCHLAKSNLC(nh2)
Modified residues
positionsymbolname
17nh2C-term amidation
Average Mass 1686.01
Monoisotopic Mass 1684.74
Isoelectric Point 11.81
Extinction Coefficient [280nm] 500.00

References
McDougal,O.M., Granum,D.M., Swartz,M., Rohleder,C. and Maupin,C.M. (2013) pKa determination of histidine residues in α-conotoxin MII peptides by 1H NMR and constant pH molecular dynamics simulation. J Phys Chem B 117:2653-2661

Internal links
Nucleic acids
Structure

External links

Tools