TxIIIA precursor (P00640) Protein Card

General Information
Name TxIIIA precursor
Alternative name(s) Tx3-T01,Tx3-T02,Tx3-T03,Tx3-T04
Organism Conus textile (Cloth-of-gold cone)
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Precursor

Classification
Conopeptide class conotoxin
Gene superfamily M superfamily
Pharmacological family

Sequence
MLKMGVVLFIFLVLFPLATLQLDA
DQPVERYAENKQLLSPD
ERREIILHALGTR
CCSWDVCDHPSCTCCG
Sequence region
[1-24]signal sequence
[55-70]mature peptideTx3a

References
Conticello,S.G., Gilad,Y., Avidan,N., Ben-Asher,E., Levy,Z. and Fainzilber,M. (2001) Mechanisms for evolving hypervariability: the case of conopeptides Mol. Biol. Evol. 18:120-131
Corpuz,G.P., Jacobsen,R.B., Jimenez,E.C., Watkins,M., Walker,C., Colledge,C., Garrett,J.E., McDougal,O., Li,W., Gray,W.R., Hillyard,D.R., Rivier,J., McIntosh,J.M., Cruz,L.J. and Olivera,B.M. (2005) Definition of the M-conotoxin superfamily: characterization of novel peptides from molluscivorous Conus venoms Biochemistry 44:8176-8186
Han,Y.H., Wang,Q., Jiang,H., Liu,L., Xiao,C., Yuan,D.D., Shao,X.X., Dai,Q.Y., Cheng,J.S. and Chi,C.W. (2006) Characterization of novel M-superfamily conotoxins with new disulfide linkage FEBS J. 273:4972-4982

Internal links
Nucleic acids Conus textile clone TxMLKM-E01 conotoxin scaffold III/IV precursor, mRNA, complete cds
Conus textile clone TxMLKM-012 conotoxin scaffold III/IV precursor, mRNA, complete cds
Conus textile M superfamily MLKM group conopeptide Tx3-T04 mRNA, complete cds.
Conus textile M superfamily MLKM group conopeptide Tx3-T01 mRNA, complete cds.
Structure

External links
UniProtKB/Swiss-Prot Q9BH73
Ncbi AEX60132, AEX60131, AEX60127, Q9BH73, AAG60511, AAG60381, AEX60133

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