prohormone-4 prepropeptide (P06730) Protein Card

General Information
Name prohormone-4 prepropeptide
Organism Conus victoriae
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Precursor

Classification
Conopeptide class unclassified
Gene superfamily
Pharmacological family

Sequence
MSSPLRMDVTFLLAAIAVTWVCG
LK
IGFPGFSTPPR
SFIQH
PKR
TLCPEDCDIASPFKCEESPTCLRLFQVCNGRWDCEHGS
DEDNALCAAVLR
PLECMIWEFLEGQRDWILPNLFNDANTDL
VAHALHEAYSMGDLQSYLNLTDQNIENIRNSTRGAIVGDPR
PLMALGMPDRAWPEVMYLLKELYNLGLDVWAE
Sequence evidence protein level
Sequence region
[1-23]signal sequence
[26-36]mature peptideprohormone-4-Vc1
[45-94]pro regionLDL receptor Class A domain
[95-196]pro region

Synthetic variants
prohormone-4-Vc1RPPTSFGPFGI

References
Robinson,S.D., Safavi-Hemami,H., McIntosh,L.D., Purcell,A.W., Norton,R.S. and Papenfuss,A.T. (2014) Diversity of Conotoxin Gene Superfamilies in the Venomous Snail, Conus victoriae. PLoS ONE 9
Robinson,S.D., Li,Q., Bandyopadhyay,P.K., Gajewiak,J., Yandell,M., Papenfuss,A.T., Purcell,A.W., Norton,R.S., Safavi-Hemami,H. (2015) Hormone-like peptides in the venoms of marine cone snails Gen. Comp. Endocrinol. [In press, corrected proof]

Internal links
Nucleic acids TSA: Conus victoriae prohormone-4 mRNA sequence.
prohormone-4 mRNA
Structure

External links
Ncbi JAI08986

Tools