RgIA [Cys2Agl,Cys8Agl] (P06774) Protein Card

General Information
Name RgIA [Cys2Agl,Cys8Agl]
Organism synthetic construct
Protein Type Synthetic
Parent RgIA

Classification
Conopeptide class conotoxin
Gene superfamily
Pharmacological family alpha conotoxin

Sequence
G(Agl)CSDPR(Agl)RYRCR
Modified residues
positionsymbolname
2AglCarbabridge [C2 unsaturated] (half)
8AglCarbabridge [C2 unsaturated] (half)
Average Mass 1536.75
Monoisotopic Mass 1535.72
Isoelectric Point 12.50
Extinction Coefficient [280nm] 1490.00

References
Chhabra,S., Belgi,A., Bartels,P., van Lierop,B.J., Robinson,S.D., Kompella,S.N., Hung,A., Callaghan,B.P., Adams,D.J., Robinson,A.J. and Norton,R.S. (2014) Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets. J. Med. Chem. 57:9933-9944

Internal links
Nucleic acids
Structure Non-reducible analogues of alpha-conotoxin RgIA: [2,8]-cis dicarba RgIA

External links

Tools