TxVIIA precursor (P00706) Protein Card

General Information
Name TxVIIA precursor
Alternative name(s) TxMEKL-031
Organism Conus textile (Cloth-of-gold cone)
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Precursor

Classification
Conopeptide class conotoxin
Gene superfamily O2 superfamily
Pharmacological family

Sequence
MEKLTILLLVAAVLMSTQAM
FQGDGEKSRKAEINFSETRKL
ARNKQKR
CGGYSTYCEVDSECCSDNCVRSYCTLF
G
Sequence region
[1-20]signal sequence
[49-75]mature peptideTxVIIA

References
Conticello,S.G., Gilad,Y., Avidan,N., Ben-Asher,E., Levy,Z. and Fainzilber,M. (2001) Mechanisms for evolving hypervariability: the case of conopeptides Mol. Biol. Evol. 18:120-131
Fainzilber,M., Gordon,D., Hasson,A., Spira,M.E. and Zlotkin,E. (1991) Mollusc-specific toxins from the venom of Conus textile neovicarius Eur. J. Biochem. 202:589-595
Nakamura,T., Yu,Z., Fainzilber,M. and Burlingame,A.L. (1996) Mass spectrometric-based revision of the structure of a cysteine-rich peptide toxin with gamma-carboxyglutamic acid, TxVIIA, from the sea snail, Conus textile Protein Sci. 5:524-530

Internal links
Nucleic acids Conus textile clone TxMEKL-031 conotoxin scaffold VI/VII precursor, mRNA, complete cds
Structure

External links
UniProtKB/Swiss-Prot Q9BPB6
Ncbi AAG60447

Tools