Ar6.6 precursor (P00735) Protein Card

General Information
Name Ar6.6 precursor
Organism Conus arenatus
Organism region Indo-Pacific
Organism diet vermivorous
Protein Type Precursor
Notes Position 13 can be a leucine or an isoleucine (uncertainty arising to cDNA sequencing).

Classification
Conopeptide class conotoxin
Gene superfamily O1 superfamily
Pharmacological family

Sequence
MKLTCVLIVAVLILTACQLIA
ADDSRDLKRFSRRKMRDGML
NTKNMKR
QCLPPLSLCTMDDDECCDDC.LFLCLVTS
Modified residues
positionsymbolname
69.Any
Sequence region
[1-21]signal sequence
[49-77]mature peptideAr6.6

References
Conticello,S.G., Gilad,Y., Avidan,N., Ben-Asher,E., Levy,Z. and Fainzilber,M. (2001) Mechanisms for evolving hypervariability: the case of conopeptides Mol. Biol. Evol. 18:120-131

Internal links
Nucleic acids Conus arenatus clone ArMKLT2-0251 conotoxin scaffold VI/VII precursor, mRNA, complete cds
Structure

External links
UniProtKB/Swiss-Prot Q9BP90
Ncbi Q9BP90, AAG60476

Tools