conantokin-G[+10O] (P07643) Protein Card

General Information
Name conantokin-G[+10O] (named by ConoServer)
Alternative name(s) ConG[+10O]
Organism synthetic construct
Protein Type Synthetic
Parent Conantokin-G

Classification
Conopeptide class conantokin
Gene superfamily
Pharmacological family

Sequence
GE(Gla)(Gla)LQ(Gla)NQO(Gla)LIR(Gla)KSN(nh2)
Modified residues
positionsymbolname
3GlaGamma carboxylic glutamic acid
4GlaGamma carboxylic glutamic acid
7GlaGamma carboxylic glutamic acid
10O4-Hydroxyproline
11GlaGamma carboxylic glutamic acid
15GlaGamma carboxylic glutamic acid
19nh2C-term amidation
Average Mass 2377.33
Monoisotopic Mass 2375.98
Isoelectric Point 2.02
Extinction Coefficient [280nm] NA

References
Kunda,S., Yuan,Y., Balsara,R.D., Zajicek,J. and Castellino,F.J. (2015) Hydroxyproline-induced Helical Disruption in Conantokin Rl-B Affects Subunit-selective Antagonistic Activities toward Ion Channels of N-Methyl-d-aspartate Receptors. J. Biol. Chem. 290:18156-18172

Internal links
Nucleic acids
Structure The Solution Structure of the Magnesium-bound Conantokin-G [+10O]

External links

Tools