Cal29b precursor (P07851) Protein Card

General Information
Name Cal29b precursor (named by ConoServer)
Alternative name(s) O1_cal29b precursor
Organism Conus californicus
Organism region Eastern Pacific
Organism diet piscivorous
Protein Type Precursor
Notes O1_cal29b was tested on a pathogen reference strain (H37Rv) and multidrug-resistant strains, having an inhibition effect on growth with a minimal inhibitory concentration (MIC)range of 3.52–0.22 M,similar concentrations to drugs used in clinics.

Classification
Conopeptide class conotoxin
Gene superfamily O1 superfamily
Cysteine framework XXIX
Pharmacological family

Sequence
MKLTCVLIVAVLILAACQFTAA
NMARYGKTQIARSDVKSID
AR
RPKCCCVCGVVGRKCCSTWKDCHPVHLPCPSSG
Sequence evidence protein level
Sequence region
[1-22]signal sequence
[23-43]pro region
[44-76]mature peptideCal29b

References
Bernáldez-Sarabia, J., Figueroa-Montiel, A., Dueñas, S., Cervantes-Luévano, K., Beltrán, J.A., Ortiz, E., Jiménez, S., Possani, L.D., Paniagua-Solís, J.F., Gonzalez-Canudas, J. and Licea-Navarro, A. (2019) The Diversified O-Superfamily in Californiconus californicus Presents a Conotoxin with Antimycobacterial Activity Toxins 11:128

Internal links
Nucleic acids
Structure

External links

Tools