Conorfamide-Vc1 [del1-14] (P08371) Protein Card

General Information
Name Conorfamide-Vc1 [del1-14] (named by ConoServer)
Alternative name(s) CNF-Vc1 (15-18)
Organism synthetic construct
Protein Type Synthetic
Parent Conorfamide-Vc1

Classification
Conopeptide class conorfamide
Gene superfamily
Pharmacological family

Sequence
FVRF(nh2)
Modified residues
positionsymbolname
5nh2C-term amidation
Average Mass 566.71
Monoisotopic Mass 566.33
Isoelectric Point 10.72
Extinction Coefficient [280nm] NA

Activity

EC50: Class A Orphans

TargetOrganismEC50Ref
MRGPRX1H. sapiens>18 μMEspino et al. (2018)

References
Espino, S.S., Robinson, S.D., Safavi-Hemami, H., Gajewiak, J., Yang, W., Olivera, B.M. and Liu, Q. (2018) Conopeptides promote itch through human itch receptor hMgprX1 Toxicon 154:28-34

Internal links
Nucleic acids
Structure

External links

Tools