PIC[O7P] (P08505) Protein Card

General Information
Name PIC[O7P]
Alternative name(s) PIC
Organism Conus purpurascens
Organism region Eastern Pacific
Organism diet piscivorous
Protein Type Wild type
Parent PIC

Classification
Conopeptide class conotoxin
Gene superfamily
Cysteine framework I
Pharmacological family alpha conotoxin

Sequence
SGCCKHPACGKNRC
Sequence evidence protein level
Average Mass 1459.69
Monoisotopic Mass 1458.57
Isoelectric Point 11.98
Extinction Coefficient [280nm] NA

Activity

Percentage inhibition: Nicotinic acetylcholine receptors

TargetOrganism% inhibitionConcentrationRef
α1β1δεR. norvegicus60+/-81 uMHoggard et al. (2017)

References
Hoggard, M.F., Rodriguez, A.M., Cano, H., Clark, E., Tae, H.S., Adams, D.J., Godenschwege, T.A. and Marí, F (2017) In vivo and in vitro testing of native α-conotoxins from the injected venom of Conus purpurascens Neuropharmacology 127:253-259

Internal links
Nucleic acids
Structure

External links

Tools