SVIE precursor (P00867) Protein Card

General Information
Name SVIE precursor
Organism Conus striatus (Striated cone)
Organism region Indo-Pacific
Organism diet piscivorous
Protein Type Precursor

Classification
Conopeptide class conotoxin
Gene superfamily O1 superfamily
Pharmacological family

Sequence
MKLTCVMIVAVLFLTTWTFVTA
DDSRYGLKNLFPKARHEMK
NPEASKLNKR
DGCSSGGTFCGIHPGLCCSEFCFLWCITFID
Sequence region
[1-22]signal sequence
[52-82]mature peptideSVIE

References
Lu,B.S., Yu,F., Zhao,D., Huang,P.T. and Huang,C.F. (1999) Conopeptides from Conus striatus and Conus textile by cDNA cloning Peptides 20:1139-1144
Kauferstein,S., Melaun,C. and Mebs,D. (2005) Direct cDNA cloning of novel conopeptide precursors of the O-superfamily Peptides 26:361-367
Bulaj,G., DeLaCruz,R., Azimi-Zonooz,A., West,P., Watkins,M., Yoshikami,D. and Olivera,B.M. (2001) Delta-conotoxin structure/function through a cladistic analysis Biochemistry 40:13201-13208
Leipold,E., Hansel,A., Olivera,B.M., Terlau,H. and Heinemann,S.H. (2005) Molecular interaction of delta-conotoxins with voltage-gated sodium channels FEBS Lett. 579:3881-3884

Internal links
Nucleic acids Conus striatus O-superfamily conotoxin SO6 precursor (SO6) mRNA, complete cds
O-Superfamily Conotoxin Peptides.
Structure

External links
UniProtKB/Swiss-Prot Q9XZK5
Ncbi CAH64847, Q9XZK5, AAD31911

Tools