SII (P00090) Protein Card

General Information
Name SII
Organism Conus striatus (Striated cone)
Organism region Indo-Pacific
Organism diet piscivorous
Protein Type Wild type
Protein precursor SII precursor (9)
SII precursor (91)
SII precursor (3900)
SII precursor (3954)

Classification
Conopeptide class conotoxin
Gene superfamily A superfamily
Cysteine framework II
Pharmacological family alpha conotoxin

Sequence
GCCCNPACGPNYGCGTSCS
Sequence evidence protein level
Average Mass 1790.95
Monoisotopic Mass 1789.51
Isoelectric Point 7.00
Extinction Coefficient [280nm] 1490.00

Activity

IC50: Nicotinic acetylcholine receptors

TargetOrganismIC50CompetitorRef
α1β1γδT. californica8uMI125-BgtxRamilo,C. et al. (1992)

References
Ramilo,C., Zafaralla,G.C., Nadasdi,L., Hammerland,L.G., Yoshikami,D., Gray,W.R., Kristipati,R., Ramachandran,J., Miljanich,G.P., Olivera,B.M. and Cruz,L.J. (1992) Novel alpha- and omega-conotoxins from Conus striatus venom Biochemistry 31:9919-9926

Internal links
Protein Precursor SII precursor (9)
SII precursor (91)
SII precursor (3900)
SII precursor (3954)
Nucleic acids
Structure

External links
Ncbi AAB23762

Tools