TxIA[beads] (P09049) Protein Card

General Information
Name TxIA[beads]
Organism synthetic construct
Protein Type Synthetic
Parent TxIA

Classification
Conopeptide class conotoxin
Gene superfamily
Cysteine framework I
Pharmacological family

Sequence
GCCSRPPCIANNPDLC(nh2)
Modified residues
positionsymbolname
17nh2C-term amidation
Sequence evidence protein level
Average Mass 1657.91
Monoisotopic Mass 1656.66
Isoelectric Point 7.00
Extinction Coefficient [280nm] NA

Activity

IC50: Nicotinic acetylcholine receptors

TargetOrganismIC50AgonistRef
α3β2R. norvegicus0 nMAch (100 uM)Wu,Y. et al. (2014)

References
Wu,Y., Wu,X., Yu,J., Zhu,X., Zhangsun,D. and Luo,S. (2014) Influence of disulfide connectivity on structure and bioactivity of α-conotoxin TxIA Molecules 19:966-979

Internal links
Nucleic acids
Structure

External links

Tools