Solution structure of the skeletal muscle and neuronal voltage gated sodium channel antagonist mu-conotoxin CnIIIC (S00150) Structure Card

General Information
Name Solution structure of the skeletal muscle and neuronal voltage gated sodium channel antagonist mu-conotoxin CnIIIC
Gene superfamily M superfamily
Cysteine framework III
Organism Conus consors
Notes
Structure type NMR
Protein Type Wild type

References
Favreau P, Benoit E, Hocking HG, Carlier L, D hoedt D, Leipold E, Markgraf R, Schlumberger S, Córdova MA, Gaertner H, Paolini-Bertrand M, Hartley O, Tytgat J, Heinemann SH, Bertrand D, Boelens R, Stöcklin R, Molgó J (2012) A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors Br J Pharmacol 166:1654-1668

Internal links
Protein CnIIIC

External links
Protein Data Bank 2YEN

3D Visualization With Jmol or gzipped file