About conotoxins

Recent key review articles

Craik DJ, Adams DJ. Chemical modification of conotoxins to improve stability and activity. ACS Chem Biol 2007,2(7):457-68. PMID: 17649970

Martinez A. Marine-derived drugs in neurology. Curr Opin Investig Drugs. 2007, 8(7):525-30. PMID: 17659472

Heinemann SH, Leipold E. Conotoxins of the O-superfamily affecting voltage-gated sodium channels. Cell Mol Life Sci. 2007, 64(11):1329-40. PMID: 17385074

Livett BG, Sandall DW, Keays D, Down J, Gayler KR, Satkunanathan N, Khalil Z. Therapeutic applications of conotoxins that target the neuronal nicotinic acetylcholine receptor. Toxicon 2006, 48(7):810-29. PMID: 16979678

Wallace MS. Ziconotide: a new nonopioid intrathecal analgesic for the treatment of chronic pain. Expert Rev Neurother 2006, 6(10):1423-8. PMID: 17078783

Schroeder CI, Doering CJ, Zamponi GW, Lewis RJ. N-type calcium channel blockers: novel therapeutics for the treatment of pain. Med Chem 2006, 2(5):535-43. PMID: 17017994

Marx UC, Daly NL, Craik DJ. NMR of conotoxins: structural features and an analysis of chemical shifts of post-translationally modified amino acids. Magn Reson Chem 2006 44 Spec No:S41-50. PMID: 16826542

Franco A, Pisarewicz K, Moller C, Mora D, Fields GB, Mari F. Hyperhydroxylation: a new strategy for neuronal targeting by venomous marine molluscs. Prog Mol Subcell Biol 2006, 43:83-103. PMID: 17153339

Janes RW. α-Conotoxins as selective probes for nicotinic acetylcholine receptor subclasses. Curr Opin Pharmacol 2005, 5(3):280-92. PMID: 15907916

Layer RT, Wagstaff JD, White HS. Conantokins: peptide antagonists of NMDA receptors. Curr Med Chem 2004, 11(23):3073-84. PMID: 15579001

French RJ, Terlau H. Sodium channel toxins--receptor targeting and therapeutic potential. Curr Med Chem 2004, 11(23):3053-64. PMID: 15578999

Livett BG, Gayler KR, Khalil Z. Drugs from the sea: conopeptides as potential therapeutics. Curr Med Chem 2004, 11(13):1715-23. PMID: 15279578

Dutertre S, Lewis RJ. Computational approaches to understand α-conotoxin interactions at neuronal nicotinic receptors. Eur J Biochem 2004, 271(12):2327-34. PMID: 15182348

Millard EL, Daly NL, Craik DJ. Structure-activity relationships of α-conotoxins targeting neuronal nicotinic acetylcholine receptors. Eur J Biochem 2004, 271(12):2320-6. PMID: 15182347

Nicke A, Wonnacott S, Lewis RJ. α-conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes. Eur J Biochem 2004, 271(12):2305-19. PMID: 15182346

Hogg RC, Bertrand D. Nicotinic acetylcholine receptors as drug targets. Curr Drug Targets CNS Neurol Disord 2004, 3(2):123-30. PMID: 15078187

Lewis RJ. Conotoxins as selective inhibitors of neuronal ion channels, receptors and transporters. IUBMB Life 2004, 56(2):89-93. PMID: 15085932

Terlau H, Olivera BM. Conus venoms: a rich source of novel ion channel-targeted peptides. Physiol Rev 2004, 84(1):41-68. PMID: 14715910