GI[ins13_GG] (P10469) Protein Card

General Information
Name GI[ins13_GG] (named by ConoServer)
Alternative name(s) GI[+13G, +14G]
Organism synthetic construct
Protein Type Synthetic
Parent GI
Notes

The toxicity of GI[ins13_GG] in mice was almost lost. The dose of 200 µg/kg of GI[ins13_GG] resulted in no death (Ma et al. 2021).


Classification
Conopeptide class conotoxin
Gene superfamily
Cysteine framework I
Pharmacological family alpha conotoxin

Sequence
ECCNPACGRHYSGGC(nh2)
Modified residues
positionsymbolname
16nh2C-term amidation
Average Mass 1551.70
Monoisotopic Mass 1550.53
Isoelectric Point 8.31
Extinction Coefficient [280nm] 1490.00

References
Ma X, Huang Q, Yu S, Xu S, Huang Y, Zhao Z, Xiao X, Dai Q. (2021) The 3/4- and 3/6-Subfamily Variants of α-Conotoxins GI and MI Exhibit Potent Inhibitory Activity against Muscular Nicotinic Acetylcholine Receptors Mar Drugs 19:705

Internal links
Nucleic acids
Structure

External links

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