SO5 precursor (P01064) Protein Card

General Information
Name SO5 precursor
Organism Conus striatus (Striated cone)
Organism region Indo-Pacific
Organism diet piscivorous
Protein Type Precursor
Notes The signal sequence and mature peptide delimitation is according Kauferstein et al (referred as conotoxin-6). and they differ from the Swiss-Prot annotation. The mature peptide delimitation in the Swiss-Prot card do not make sense because one of the cysteine is indicated as beeing outside the mature peptide but is also implicated in one disulfide bond in the mature.

Classification
Conopeptide class conotoxin
Gene superfamily O1 superfamily
Pharmacological family

Sequence
MKLTCVVIIAVLLLTACQLITADDS
RGVQKHRSLRSTTKVS
K
STSCMEAGSYCGSTTRICCGYCAYFGKKCIDYPSN
Sequence region
[1-25]signal sequence
[43-77]mature peptideSO5

References
Kauferstein,S., Melaun,C. and Mebs,D. (2005) Direct cDNA cloning of novel conopeptide precursors of the O-superfamily Peptides 26:361-367

Internal links
Nucleic acids Conus striatus mRNA for four-loop conotoxin preproprotein, clone 6
Structure

External links
UniProtKB/Swiss-Prot Q5K0D3
Ncbi Q5K0D3, CAH64848

Tools