Conotoxin-12 precursor (P01067) Protein Card

General Information

Name	Conotoxin-12 precursor
Organism	Conus vexillum
Organism region	Indo-Pacific
Organism diet	vermivorous
Protein Type	Precursor

Classification

Conopeptide class	conotoxin
Gene superfamily	O1 superfamily
Pharmacological family

Sequence

MKLTCVLIITVLFLTASQLITADYS RDQRQYRAVRLGDEMR NFKGAR DCGGQGKGCYTQPCCPGLRCRGGGTGGGVCQP
Sequence region	[1-25] signal sequence [48-79] mature peptide Conotoxin-12

References

Kauferstein,S., Melaun,C. and Mebs,D. (2005) Direct cDNA cloning of novel conopeptide precursors of the O-superfamily Peptides 26:361-367

Internal links

Nucleic acids	Conus vexillum mRNA for four-loop conotoxin preproprotein, clone 12
Structure

External links

UniProtKB/Swiss-Prot	Q5K0D0
Ncbi	Q5K0D0, CAH64851

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Monday 27 March 2023