PVIA precursor (P01563) Protein Card

General Information
Name PVIA precursor
Organism Conus purpurascens
Organism region Eastern Pacific
Organism diet piscivorous
Protein Type Precursor

Classification
Conopeptide class conotoxin
Gene superfamily O1 superfamily
Pharmacological family

Sequence
MKLTCVMIVAVLFLTAWTFVTA
DDSKNGLENHFWKARDEMK
NREASKLDKK
EACYAPGTFCGIKPGLCCSEFCLPGVCFG
G
Sequence region
[1-22]signal sequence
[52-80]mature peptidePVIA

References
Terlau,H., Shon,K.J., Grilley,M., Stocker,M., Stuhmer,W. and Olivera,B.M. (1996) Strategy for rapid immobilization of prey by a fish-hunting marine snail Nature 381:148-151
Bulaj,G., DeLaCruz,R., Azimi-Zonooz,A., West,P., Watkins,M., Yoshikami,D. and Olivera,B.M. (2001) Delta-conotoxin structure/function through a cladistic analysis Biochemistry 40:13201-13208
Shon,K.J., Grilley,M.M., Marsh,M., Yoshikami,D., Hall,A.R., Kurz,B., Gray,W.R., Imperial,J.S., Hillyard,D.R. and Olivera,B.M. (1995) Purification, characterization, synthesis, and cloning of the lockjaw peptide from Conus purpurascens venom Biochemistry 34:4913-4918

Internal links
Nucleic acids Sequence 9 from patent US 5739276
O-Superfamily Conotoxin Peptides.
Structure

External links
UniProtKB/Swiss-Prot P58913
Ncbi P58913, 2110216A

Tools