VilXIVA (P01619) Protein Card

General Information
Name VilXIVA
Alternative name(s) Vil14a
Organism Conus villepinii
Organism region Western Atlantic and Caribbean
Organism diet vermivorous
Protein Type Wild type
Protein precursor VilXIVA precursor (7651)
VilXIVA precursor (8490)
Notes Based on an experimemtal structure (unreleased NMR structure), VilXIVA has been suggested to be part of the kappa family (potassium channel blocker) (Moller et al. 2005).

Conopeptide class conotoxin
Gene superfamily R superfamily
Cysteine framework XIV
Pharmacological family

Sequence evidence protein level
Average Mass 2873.35
Monoisotopic Mass 2871.21
Isoelectric Point 11.81
Extinction Coefficient [280nm] 2980.00

Moller,C., Rahmankhah,S., Lauer-Fields,J., Bubis,J., Fields,G.B. and Mari,F. (2005) A novel conotoxin framework with a helix-loop-helix (Cs alpha/alpha) fold Biochemistry 44:15986-15996
Möller, C., Dovell, S., Melaun, C. and Marí, F. (2018) Definition of the R-superfamily of conotoxins: Structural convergence of helix-loop-helix peptidic scaffolds Peptides 107:75-82

Internal links
Protein Precursor VilXIVA precursor (7651)
VilXIVA precursor (8490)
Nucleic acids
Structure NMR Solution Structure of vil14a

External links
UniProtKB/Swiss-Prot P84704
Ncbi P84704, 6EFE_A