Lt1.2 (P02666) Protein Card

General Information
Name Lt1.2
Alternative name(s) LeD2,Lt1b
Organism Conus litteratus
Organism region Indo-Pacific
Organism diet vermivorous
Protein Type Wild type
Protein precursor Lt1.2 precursor (544)
Lt1.2 precursor (512)
Lt1.2 precursor (9807)
Notes This sequence was directly derived from the precursor: some post-translational modifications may be missing.

Classification
Conopeptide class conotoxin
Gene superfamily A superfamily
Cysteine framework I
Pharmacological family

Sequence
GCCARAACAGIHQELCG(nh2)
Modified residues
positionsymbolname
18nh2C-term amidation
Sequence evidence nucleic acid level
Average Mass 1657.91
Monoisotopic Mass 1656.67
Isoelectric Point 8.31
Extinction Coefficient [280nm] NA

References
Pi,C., Liu,J., Peng,C., Liu,Y., Jiang,X., Zhao,Y., Tang,S., Wang,L., Dong,M., Chen,S. and Xu,A. (2006) Diversity and evolution of conotoxins based on gene expression profiling of Conus litteratus Genomics 88:809-819
Luo,S., Zhangsun,D., Zhang,B., Quan,Y. and Wu,Y. (2006) Novel alpha-conotoxins identified by gene sequencing from cone snails native to Hainan, and their sequence diversity J. Pept. Sci. 12:693-704
Zhang, H., Fu, Y., Wang, L., Liang, A., Chen, S. and Xu, A. (2019) Identifying novel conopepetides from the venom ducts of Conus litteratus through integrating transcriptomics and proteomics Journal of proteomics 192:346-357
Li,X., Chen,W., Zhangsun,D. and Luo,S. (2020) Diversity of Conopeptides and Their Precursor Genes of Conus Litteratus. Mar Drugs 18

Internal links
Protein Precursor Lt1.2 precursor (544)
Lt1.2 precursor (512)
Lt1.2 precursor (9807)
Nucleic acids
Structure

External links
Ncbi AAZ85381, ABC74973

Tools