Gla-MrIII (P02692) Protein Card

General Information
Name Gla-MrIII
Alternative name(s) Mr077,Mr5.2
Organism Conus marmoreus
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Wild type
Protein precursor Gla-MrIII precursor (857)
Gla-MrIII precursor (5472)

Classification
Conopeptide class conotoxin
Gene superfamily T superfamily
Cysteine framework V
Pharmacological family

Sequence
FCCRTQ(Gla)VCC(Gla)AIKN(nh2)
Modified residues
positionsymbolname
7GlaGamma carboxylic glutamic acid
11GlaGamma carboxylic glutamic acid
16nh2C-term amidation
Sequence evidence protein level
Average Mass 1830.04
Monoisotopic Mass 1828.70
Isoelectric Point 7.00
Extinction Coefficient [280nm] NA

References
Han,Y.H., Wang,Q., Jiang,H., Miao,X.W., Chen,J.S. and Chi,C.W. (2005) Sequence diversity of T-superfamily conotoxins from Conus marmoreus Toxicon 45:481-487
Hansson,K., Furie,B., Furie,B.C. and Stenflo,J. (2004) Isolation and characterization of three novel Gla-containing Conus marmoreus venom peptides, one with a novel cysteine pattern Biochem. Biophys. Res. Commun. 319:1081-1087
Dutertre,S., Jin,A.H., Kaas,Q., Jones,A., Alewood,P.F. and Lewis,R.J. (2013) Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom. Mol. Cell Proteomics 12:312-329

Internal links
Protein Precursor Gla-MrIII precursor (857)
Gla-MrIII precursor (5472)
Nucleic acids
Structure

External links
Ncbi Q6PN84, AAT01630

Tools